I had a brower hijack, it forced my browser into some adware search site, overwrote google, etc all the typical hijack stuff.. but I removed it by hand, it was a bitch, but do-able none the less, you just need alot of techincal pc skills \ resources, or you could do more damage than was done
however I still use IE or my own web browser that I programmed, but its more of an IE wrapper than a full fleged browser, because it uses IE's core, that isnt affted by hijacks, yet still can trigger them. Whatever, I like my combo, and should a hijacker come a knocking, it'll get its ass kicked by me.
But you see, I HAVE removed quite a few Hijacks using the registry editor, but the spread SO fast. It becomes a 30 minute ordeal.